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A Guide To Understanding The Risks Associated With Hormone Replacement Therapy (HRT) For Women

Updated: Feb 26



What are the risks of HRT

It is absolutely essential to understand as much as possible about Hormone Replacement Therapy (HRT) before deciding on the right treatment plan for you. In our article here, we've outlined some of the potential benefits of HRT, but it is equally important that you explore the potential risks associated with HRT - in today's article, we aim to explore the potential risks of HRT and provide insights on some of the considerations your should keep in mind when contemplating this treatment option.


What Is Hormone Replacement Therapy?


Hormone Replacement Therapy (HRT) is a treatment where hormones, like oestrogen or testosterone, are given to help balance out levels in your body. It's used in many cases to manage symptoms of menopause, like hot flashes and mood swings. HRT can come in various forms like pills, patches, creams, or injections, and it's usually tailored to each person's specific needs. Overall, it's about restoring hormonal balance to improve quality of life. To learn more about HRT in Australia, check out our article here.


What Are The Risks of Hormone Replacement Therapy (HRT)


As women approach menopause, Hormone Replacement Therapy (HRT) emerges as a potential solution to alleviate symptoms and promote overall well-being. While HRT offers various benefits, it's essential to understand and navigate the associated risks effectively.

While HRT offers various benefits, it's essential to understand and navigate the associated risks effectively.

Potential Risks of HRT


  1. Cardiovascular Risks: Some studies suggest that HRT may increase the risk of cardiovascular events, including heart disease and stroke, particularly in older women or those with pre-existing cardiovascular conditions. It's essential to assess individual cardiovascular risk factors and discuss them with your healthcare provider before starting HRT.

  2. Cancer Risk: Oestrogen-progestin combination therapy has been associated with an increased risk of breast cancer in some women. Additionally, oestrogen-alone therapy may elevate the risk of endometrial cancer in women who have not undergone a hysterectomy. Regular monitoring and screening for breast and uterine cancer are essential for women undergoing HRT.

  3. Thromboembolic Events: HRT, especially oral oestrogen formulations, may elevate the risk of blood clots, leading to thromboembolic events such as deep vein thrombosis (DVT) and pulmonary embolism (PE). Women with a history of thromboembolic events or predisposing factors for blood clots should exercise caution when considering HRT.

  4. Gallbladder Disease: Some studies suggest a potential association between HRT and an increased risk of gallbladder disease, including gallstones. Women considering HRT should discuss their risk factors for gallbladder disease with their healthcare provider to make informed decisions about treatment.


To learn more about the risk of HRT, we recommend you consult your healthcare provider (The Functional Doctors or another provider) and review the content available on https://www.healthdirect.gov.au/hormone-replacement-therapy


What to Consider When Contemplating HRT


  • Individual Health Status: Before initiating HRT, it's essential to assess your individual health status, including medical history, family history, and current health conditions. Discuss any pre-existing health conditions or risk factors with your healthcare provider to determine if HRT is a suitable treatment option for you.


Discuss any pre-existing health conditions or risk factors with your healthcare provider to determine if HRT is a suitable treatment option for you.
  • Age and Menopausal Stage: The risks and benefits of HRT may vary depending on your age and stage of menopause. Younger women and those who initiate HRT closer to the onset of menopause may experience more significant benefits with fewer risks compared to older women.


  • Treatment Duration and Dosage: Healthcare providers typically recommend using the lowest effective dose of HRT for the shortest duration necessary to manage symptoms. Discuss the optimal duration and dosage of HRT with your healthcare provider to minimise potential risks while maximising benefits.


  • Regular Monitoring and Follow-Up: Regular monitoring and follow-up appointments are crucial for women undergoing HRT. Your healthcare provider will assess your response to treatment, monitor for potential side effects, and adjust your treatment plan as needed to optimise outcomes and minimise risks.


Conclusion

While Hormone Replacement Therapy (HRT) offers benefits for managing menopausal symptoms and promoting overall health (see our article on potential benefits here), it's essential to carefully consider the potential risks alongside benefits before initiating treatment. 


By discussing your individual health status, risk factors, and treatment goals with your healthcare provider, you can make informed decisions about whether HRT is the right option for you. Stay informed, stay proactive, and prioritise your well-being throughout your menopausal journey. 


If you are a woman over 45 and would like to learn more about HRT and assess your suitability, you can schedule a free appointment with our patient-management team using the link below.


 
 


While we've ensured that everything you read on our blogs is medically reviewed and approved, the information is not intended as a substitute for professional medical advice, diagnosis, or treatment. You should never rely on this blog for specific medical advice, and if you have any questions or concerns specific to your personal case, you should speak to your doctor or reach out to our team directly.



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